Hiroshi Nakase
Sapporo Medical University
Internal medicineSurgeryPathologyImmunologyColitisInflammationInfliximabInflammatory bowel diseaseDiseaseCrohn's diseaseUlcerative colitisIn patientHepatologyRefractoryCancer researchColorectal cancerMedicineBiologyImmune systemGastroenterology
Publications 455
#1Tsukasa Yamakawa (Sapporo Medical University)H-Index: 3
#2Keisuke Ishigami (Sapporo Medical University)H-Index: 11
Last. Hiro-o Yamano (Sapporo Medical University)H-Index: 24
view all 18 authors...
#1Masahiro ShitaniH-Index: 5
#2Jiro OginoH-Index: 10
view all 11 authors...
#1Katsuyoshi Ando (Asahikawa Medical University)H-Index: 7
#2Mikihiro Fujiya (Asahikawa Medical University)H-Index: 28
Last. Masakazu Nagahori (Tokyo Medical and Dental University)H-Index: 18
view all 34 authors...
The mortality and risk factors of severe disease and death due to arterial and venous thromboembolism (ATE and VTE, respectively) in patients with inflammatory bowel disease (IBD) remain unclear, especially in Asia. This study aimed to reveal the mortality and risk factors of TE in IBD patients in Japan. In the primary surveillance, responses to questionnaires regarding the number of cases of severe TE and TE-associated death in IBD patients in a span of over the past 10 years were obtained from...
#1Kohei Wagatsuma (Sapporo Medical University)H-Index: 6
#2Kotaro Akita (Sapporo Medical University)
Last. Yoshiharu Masaki (Sapporo Medical University)H-Index: 7
view all 15 authors...
Rationale null Mixed neuroendocrine non-neuroendocrine neoplasm (MiNEN) is a rare tumor. MiNEN of the gallbladder (GB) with pancreaticobiliary maljunction (PMJ) is extremely rare. The origin of MiNEN of the GB remains unknown; the biliary tract normally lacks neuroendocrine cells. MiNEN of the GB has a poor prognosis; because of its rarity, no treatment or management guidelines have been established yet. null Patient concerns null A 47-year-old male presenting with right hypochondrial pain and m...
#1Miki Miura (Kyorin University)H-Index: 4
#2Hirotaka ShimizuH-Index: 6
Last. Itaru IwamaH-Index: 3
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The Epstein–Barr virus (EBV) infection status in patients with inflammatory bowel disease (IBD), particularly those using thiopurines, may be associated with the risk of lymphoproliferative disorder and hemophagocytic lymphohistiocytosis. This was the first multicenter survey of EBV infection in Japanese patients with IBD. Factors related to the EBV infection status were also investigated. Five tertiary institutions in Japan participated in this study to examine pediatric and adult patients with...
#1Masashi Idogawa (Sapporo Medical University)H-Index: 22
#2Masayo Koizumi (Sapporo Medical University)
Last. Takashi Tokino (Sapporo Medical University)H-Index: 81
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We often encounter situations in which data from the TCGA that have been analyzed in papers we read or reviewed cannot be reproduced, even when TCGA datasets are used, especially in survival analyses. Therefore, we attempted to confirm the data source for TCGA survival analysis and found that several websites used to analyze the survival data of TCGA datasets inappropriately handle the survival data, causing differences in statistical analyses. This causes the misinterpretation of results becaus...
#1Yasunao Numata (Sapporo Medical University)H-Index: 1
#2Shigeru Sasaki (Sapporo Medical University)H-Index: 21
Last. Hiroshi Nakase (Sapporo Medical University)H-Index: 48
view all 8 authors...
#1Yoshihiro YokoyamaH-Index: 7
#2Noriyuki Akutsu (Sapporo Medical University)H-Index: 7
Last. Yoshiaki ArimuraH-Index: 32
view all 12 authors...
Thus far, there have been limited case reports on immunoglobulin G4-related autoimmune hepatitis (IgG4-AIH), and its clinical features have not been elucidated. We herein report a rare case of IgG4-AIH simultaneously concomitant with autoimmune pancreatitis (AIP). A 73-year-old female was admitted to our hospital for further investigation of elevated levels of liver transaminase and pancreatic enzymes. Her serological tests showed a high antinuclear antibody titer, and elevated IgG and IgG4 leve...
#1Yasuhiro Shibata (Sapporo Medical University)
#2Keisuke Ishigami (Sapporo Medical University)H-Index: 11
Last. Hiroshi Nakase (Sapporo Medical University)H-Index: 48
view all 8 authors...
An 86-year-old woman was admitted to our hospital with anemia. She had never experienced symptoms of serositis. Colonoscopy revealed colitis with erosions and a friable mucosa. First, she was diagnosed with unclassified inflammatory bowel disease (IBD-U). We suspected familial Mediterranean fever as a differential diagnosis of IBD-U, and MEFV gene analysis showed heterozygosity for Exon2 R202Q. The patient was treated with colchicine 0.5 mg. After 4 months, a follow-up colonoscopy showed remarka...
#1Yoshiharu Masaki (Sapporo Medical University)H-Index: 7
#2Hiroshi Nakase (Sapporo Medical University)H-Index: 48
Last. Yuzo Kodama (Kobe University)H-Index: 35
view all 14 authors...
The effectiveness of azathioprine (AZA) in preventing relapse and maintaining autoimmune pancreatitis (AIP) remission has been reported; however, most of these studies are case series with no randomized control trials available in the literature. Therefore, this study performed a systematic review and meta-analysis of the existing literature on this subject to determine the clinical efficacy of AZA as maintenance therapy for AIP patients. A systematic search was performed to identify studies on ...