Genetic analysis in European ancestry individuals identifies 517 loci associated with liver enzymes
Abstract
Serum concentration of hepatic enzymes are linked to liver dysfunction, metabolic and cardiovascular diseases. We perform genetic analysis on serum levels of alanine transaminase (ALT), alkaline phosphatase (ALP) and gamma-glutamyl transferase (GGT) using data on 437,438 UK Biobank participants. Replication in 315,572 individuals from European descent from the Million Veteran Program, Rotterdam Study and Lifeline study confirms 517 liver enzyme...
Paper Details
Title
Genetic analysis in European ancestry individuals identifies 517 loci associated with liver enzymes
Published Date
May 10, 2021
Journal
Volume
12
Issue
1
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