Improved antimicrobial activity and oral bioavailability of delafloxacin by self-nanoemulsifying drug delivery system (SNEDDS)
Volume: 64, Pages: 102572 - 102572
Published: Aug 1, 2021
Abstract
In the current study, a novel self-nanoemulsifying drug delivery system (SNEDDS) was developed in order to improve the oral bioavailability of delafloxacin (DLF). Various oils, surfactants and co-surfactants were screened by solubility studies. Based on solubilization, potential of DLF in various vehicles, Lauroglycol™-90 (oil), Tween® 80 (surfactant) and Transcutol®-HP (co-surfactant) were selected for the development of DLF loaded SNEDDS...
Paper Details
Title
Improved antimicrobial activity and oral bioavailability of delafloxacin by self-nanoemulsifying drug delivery system (SNEDDS)
Published Date
Aug 1, 2021
Volume
64
Pages
102572 - 102572
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