iPSC-derived myelinoids to study myelin biology of humans

Volume: 56, Issue: 9, Pages: 1346 - 1358.e6
Published: May 1, 2021
Abstract
Myelination is essential for central nervous system (CNS) formation, health, and function. Emerging evidence of oligodendrocyte heterogeneity in health and disease and divergent CNS gene expression profiles between mice and humans supports the development of experimentally tractable human myelination systems. Here, we developed human iPSC-derived myelinating organoids ("myelinoids") and quantitative tools to study myelination from...
Paper Details
Title
iPSC-derived myelinoids to study myelin biology of humans
Published Date
May 1, 2021
Volume
56
Issue
9
Pages
1346 - 1358.e6
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