Neuroendocrine changes in the hypothalamic‐neurohypophysial system in the Wistar audiogenic rat (WAR) strain submitted to audiogenic kindling
Abstract
The Wistar audiogenic rat (WAR) strain is used as an animal model of epilepsy, which when submitted to acute acoustic stimulus presents tonic-clonic seizures, mainly dependent on brainstem (mesencephalic) structures. However, when WARs are exposed to chronic acoustic stimuli (audiogenic kindling-AK), they usually present tonic-clonic seizures, followed by limbic seizures, after recruitment of forebrain structures such as the cortex, hippocampus...
Paper Details
Title
Neuroendocrine changes in the hypothalamic‐neurohypophysial system in the Wistar audiogenic rat (WAR) strain submitted to audiogenic kindling
Published Date
May 4, 2021
Volume
33
Issue
7
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