Novel Glutamatergic Modulators for the Treatment of Mood Disorders: Current Status
Abstract
The efficacy of standard antidepressants is limited for many patients with mood disorders such as major depressive disorder (MDD) and bipolar depression, underscoring the urgent need to develop novel therapeutics. Both clinical and preclinical studies have implicated glutamatergic system dysfunction in the pathophysiology of mood disorders. In particular, rapid reductions in depressive symptoms have been observed in response to subanesthetic...
Paper Details
Title
Novel Glutamatergic Modulators for the Treatment of Mood Disorders: Current Status
Published Date
Apr 26, 2021
Journal
Volume
35
Issue
5
Pages
527 - 543
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