Proton beam therapy for children and adolescents and young adults (AYAs): JASTRO and JSPHO Guidelines.

Published on Apr 16, 2021in Cancer Treatment Reviews8.885
· DOI :10.1016/J.CTRV.2021.102209
Masashi Mizumoto28
Estimated H-index: 28
,
Hiroshi Fuji14
Estimated H-index: 14
+ 33 AuthorsHideyuki Sakurai32
Estimated H-index: 32
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Abstract
Abstract Children and adolescents and young adults (AYAs) with cancer are often treated with a multidisciplinary approach. This includes use of radiotherapy, which is important for local control, but may also cause adverse events in the long term, including second cancer. The risks for limited growth and development, endocrine dysfunction, reduced fertility and second cancer in children and AYAs are reduced by proton beam therapy (PBT), which has a dose distribution that decreases irradiation of normal organs while still targeting the tumor. To define the outcomes and characteristics of PBT in cancer treatment in pediatric and AYA patients, this document was developed by the Japanese Society for Radiation Oncology (JASTRO) and the Japanese Society of Pediatric Hematology/Oncology (JSPHO).
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