Higher body mass index associated with smaller frontal cortical volumes in older adult patients with bipolar disorder

Patients with bipolar disorder (BD) tend to have accelerated decline in executive function during the aging. Thus far, only few studies have examined the effect of obesity on frontal cortical volumes in young patients with BD. Herein we aimed to ascertain the association between body mass index (BMI) and frontal cortical volumes in older adult patients with BD. We recruited outpatients who were diagnosed as bipolar I disorder (BD-I) and aged...