Asymmetric Total Synthesis of Norzoanthamine

We report herein the asymmetric total synthesis of norzoanthamine using radical reactions as key steps for rapid access to the congested carbocyclic core, which is the major synthetic challenge for most zoanthamine alkaloids. (1) The Ueno–Stork radical cyclization was applied to construct the adjacent quaternary centers at the C‐9 and C‐22 positions; (2) a Co‐catalyzed HAT radical reaction was successfully applied to construct the quaternary...