SARS-CoV-2 and Burkholderia cenocepacia infection in a patient with Cystic Fibrosis: An unfavourable conjunction?

C. Olcese; Rosaria Casciaro; D. Pirlo; C. Debbia; Elio Castagnola; Federico Cresta; Carlo Castellani

doi:https://doi.org/10.1016/j.jcf.2021.03.024

doi.org/10.1016/j.jcf.2021.03.024

SARS-CoV-2 and Burkholderia cenocepacia infection in a patient with Cystic Fibrosis: An unfavourable conjunction?

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..., Carlo Castellani

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Journal of Cystic Fibrosis5.20

Volume: 20, Issue: 3, Pages: e29 - e31

Published: May 1, 2021

Abstract

The effects of the concomitant infection by COVID-19 and Burkholderia cepacia (Bc) in CF are not known. We describe the case of a 34 years woman with CF, colonized by Bc and found SARS-CoV2 positive. In the first hospital week she suffered acute respiratory failure and chest imaging showed interstitial involvement and multiple thickenings. She was treated with antibiotics, dexamethasone, remdesivir and heparin, with gradual improvement and...