Original paper
Implications for preeclampsia: hypoxia-induced Notch promotes trophoblast migration
Abstract
In the first trimester of human pregnancy, low oxygen tension or hypoxia is essential for proper placentation and placenta function. Low oxygen levels and activation of signaling pathways have been implicated as critical mediators in the promotion of trophoblast differentiation, migration, and invasion with inappropriate changes in oxygen tension and aberrant Notch signaling both individually reported as causative to abnormal placentation....
Paper Details
Title
Implications for preeclampsia: hypoxia-induced Notch promotes trophoblast migration
Published Date
Jun 1, 2021
Journal
Volume
161
Issue
6
Pages
681 - 696
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Notes
History