Regulation of ferroptosis by bioactive phytochemicals: Implications for medical nutritional therapy
Abstract
Ferroptosis is an iron- and lipotoxicity-dependent regulated cell death that has been implicated in various diseases, such as cancer, neurodegeneration and stroke. The biosynthesis of phospholipids, coenzyme Q10, and glutathione, and the metabolism of iron, amino acids and polyunsaturated fatty acid, are tightly associated with cellular sensitivity to ferroptosis. Up to now, only limited drugs targeting ferroptosis have been documented and...
Paper Details
Title
Regulation of ferroptosis by bioactive phytochemicals: Implications for medical nutritional therapy
Published Date
Jun 1, 2021
Journal
Volume
168
Pages
105580 - 105580
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