MiR-93/HMGB3 regulatory axis exerts tumor suppressive effects in colorectal carcinoma cells

MicroRNA (miR)-93 has been proven to mediate the initiation and progression of colorectal carcinoma (CRC); however, the mechanisms by which miR-93 mediates CRC development need deeper elucidation. The present study is designed to investigate the association between miR-93 and high mobility group box 3 (HMGB3), as well as the functions of miR-93, in CRC. miR-93 expression was quantified by RT-qPCR. CRC cells were transfected or cotransfected with...