Original paper
Glycolysis and Fatty Acid Oxidation Inhibition Improves Survival in Glioblastoma
Abstract
Glioblastoma (GBM) is the most aggressive adult glioma with a median survival of 14 months. While standard treatments (safe maximal resection, radiation, and temozolomide chemotherapy) have increased the median survival in favorable O(6)-methylguanine-DNA methyltransferase (MGMT)-methylated GBM (~21 months), a large proportion of patients experience a highly debilitating and rapidly fatal disease. This study examined GBM cellular energetic...
Paper Details
Title
Glycolysis and Fatty Acid Oxidation Inhibition Improves Survival in Glioblastoma
Published Date
Mar 29, 2021
Journal
Volume
11
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Notes
History