Original paper
Resolvin D1 suppresses inflammation‐associated tumorigenesis in the colon by inhibiting IL‐6‐induced mitotic spindle abnormality
Abstract
While failure in resolution of inflammation is considered to increase the risk of tumorigenesis, there is paucity of experimental as well as clinical evidence supporting this association. Resolvin D1 (RvD1) is a representative pro-resolving lipid mediator that is endogenously generated from docosahexaenoic acid for the resolution of inflammation. Here, we report a decreased level of RvD1 in the blood from colorectal cancer patients and mice...
Paper Details
Title
Resolvin D1 suppresses inflammation‐associated tumorigenesis in the colon by inhibiting IL‐6‐induced mitotic spindle abnormality
Published Date
Apr 1, 2021
Journal
Volume
35
Issue
5
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Notes
History