Cabozantinib (Cabo) beyond progression improves survival in advanced renal cell carcinoma patients: The CABEYOND study (Meet-Uro 21).

320 Background: The multikinase inhibitor cabozantinib (Cabo) is an effective treatment option for metastatic renal cell carcinoma (mRCC). However, data on the optimal sequencing of Cabo and other available therapies are lacking. In particular, the strategy of continuing Cabo administration after disease progression (PD) has never been investigated yet. In light of its ability of inhibiting MET and AXL, which are implied in VEGFR acquired...