Tannic Acid as a Natural Ferroptosis Inhibitor: Mechanisms and Beneficial Role of 3’‐O‐Galloylation

Ferroptosis is a recently reported cellular apoptosis form. Screening for safe ferroptosis inhibitors and elucidation of the mechanisms have recently attracted significant attention. In this study, the ferroptosis‐inhibitory activities of gallotannin tannic acid and its parent, 1,2,3,4,6‐penta‐ O ‐galloyl‐ β ‐D‐glucopyranose ( β ‐PGG), were comparatively evaluated using an erastin‐mediated bone marrow‐derived mesenchymal stem cell (bmMSC) model,...