Original paper
Epigenetics, 1-Carbon Metabolism, and Homocysteine During Dysbiosis
Abstract
Although a high-fat diet (HFD) induces gut dysbiosis and cardiovascular system remodeling, the precise mechanism is unclear. We hypothesize that HFD instigates dysbiosis and cardiac muscle remodeling by inducing matrix metalloproteinases (MMPs), which leads to an increase in white adipose tissue, and treatment with lactobacillus (a ketone body donor from lactate; the substrate for the mitochondria) reverses dysbiosis-induced cardiac injury, in...
Paper Details
Title
Epigenetics, 1-Carbon Metabolism, and Homocysteine During Dysbiosis
Published Date
Feb 23, 2021
Journal
Volume
11
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Notes
History