Purpose to compare single-step transepithelial PRK (TPRK) to conventional alcohol assisted epithelial removal then PRK (AAPRK) regarding pain, epithelial healing, visual acuity, corneal haze measured subjectively and objectively, higher order aberrations changes, contrast sensitivity and vector analysis of astigmatic correction with one year follow-up. Patients and methods a prospective double-blind randomized study of 29 subjects (58 eyes) who underwent myopic aberration-free laser correction by Smart Pulse Technology using Schwind Amaris 1050Hz (SCHWIND eye-tech-solutions GmbH, Kleinostheim, Germany) with one year follow-up. Right eye was randomly treated by AAPRK or TPRK. Postoperative assessment was performed on day 1 and 3, at 1st week, and 1st, 3rd, 6th and 12th months. Patients were assessed for pain, epithelial healing, visual acuity, corneal haze, astigmatic correction, higher order aberrations and contrast sensitivity. Results Epithelial healing was complete by the third day in 62.1% of AAPRK eyes and in 89.7% of TPRK eyes. First day postoperative pain was higher in TPRK group (P= 0.0134). The Decimal uncorrected visual acuity at 12 months was 1.47±0.39 and 1.57±0.38 in the AAPRK and TPRK groups respectively (P= 0.3719). Post-PRK haze reached a final level of 0.04±0.14 and 0.02±0.1 in AAPRK and TPRK groups respectively (P= 0.5607). Contrast sensitivity was comparable in low and high frequency cycles per degree. Vector analysis of astigmatic correction showed correction index at one year of 0.99 and 1.05 for AAPRK and TPRK groups respectively. Conclusion Alcohol assisted and transepithelial PRK have comparable results regarding safety and efficacy.
#2Wenbo Cheng(First Affiliated Hospital of Xinjiang Medical University)H-Index: 2
Last. Yan Wang(Tianjin Medical University)H-Index: 16
view all 17 authors...
Purpose To investigate the differential expression of cytokines and growth factors in the cornea and aqueous humor after small incision lenticule extraction (SMILE) compared with femtosecond LASIK (FS-LASIK) using rabbit model. Methods Sixteen eyes of 16 rabbits in each group underwent SMILE or FS-LASIK with refractive correction of -6.00 DS/-1.00 DC. Eight additional rabbits served as controls. Pre- and 24 hours, 1 week, 1 month, and 3 months postoperatively, slit-lamp and anterior segment opti...
Abstract Purpose To investigate immediate and short-term visual recovery in a large cohort of 2093 myopic eyes (with or without astigmatism) treated with SmartSurfACE procedure, a combination of Transepithelial Photo Refractive Keratectomy (PRK) and Smart Pulse Technology (SPT, SCHWIND eye-tech-solutions GmbH, Kleinostheim, Germany). Methods In this retrospective case series, post-operative outcomes were evaluated immediately after the surgery (Day 0), at day 1 and 3 months postoperatively, afte...
Last. Maliheh Karimpour(MUMS: Mashhad University of Medical Sciences)H-Index: 1
view all 4 authors...
Abstract Purpose To compare clinical outcomes between mechanical debridement photorefractive keratectomy (m-PRK) and trans-epithelial photorefractive keratectomy (t-PRK) in myopic patients. Methods Eighty eyes of 40 myopic patients with age between 18 and 55 years were included in this study. In each patient, one eye was randomly assigned for t-PRK, using the Amaris laser's ORK-CAM software and the other eye for m-PRK, using a spatula. Stromal ablation was done by Schwind Amaris 750S. Uncorrecte...
Purpose. The aim of the study was to compare visual acuity, refractive results, safety, and efficacy of TPRK with AAPRK as primary outcomes and surgical time, pain scores, haze levels, and healing time as secondary outcomes in TPRK and AAPRK groups. Setting. Security Forces Hospital, Ophthalmology Department, Riyadh, Kingdom of Saudi Arabia. Design. Prospective, nonrandomized case-control comparative study. Methods. A total of 200 eyes of 100 consecutive patients were included. One hundred eyes ...
Background Standardization for reporting medical outcomes facilitates clinical study comparisons and has a fundamental role on research reproducibility. In this context, we present AstigMATIC, a free standalone application for automated standardized astigmatism vector analyses in corneal and intraocular refractive surgeries. AstigMATIC uses a simple graphical user interface (GUI) and allows the simultaneous display and analysis of astigmatism magnitude and axis.
PURPOSE: To compare visual outcomes and postoperative aberrations after surface ablation performed with a 750-Hz versus a 1,050-Hz excimer laser coupled with an ablation software designed to reduce corneal surface irregularity. METHODS: Retrospective comparative trial of myopic eyes that had refractive surgery consecutively treated with transepithelial advanced surface ablation with a 750-Hz excimer laser (750 group) versus a 1,050-Hz excimer laser coupled with the Smart Pulse Technology ablatio...
Transepithelial photorefractive keratectomy (tPRK), where both the epithelium and stroma are removed in a single-step, is a relatively new procedure of laser refractive error correction. This study compares the 3-month results of myopia and compound myopic astigmatism correction by tPRK or conventional alcohol-assisted PRK (aaPRK). This prospective, nonrandomized, case–control study recruited 148 consecutive patients; 93 underwent tPRK (173 eyes) and 55 aaPRK (103 eyes). Refractive results, pred...
Purpose The aim of the study was to compare both transepithelial photorefractive keratectomy (trans-PRK) and PRK for correction of mild and moderate myopia with respect to effectiveness, visual recovery pain, and safety. Materials and methods In this prospective case-control series, group I with 24 myopic eyes (12 patients) with spherical equivalent -1.00 to -6.00 D underwent trans-PRK using Schwind Amaris 500E excimer laser, with trans-PRK plate form. A case-adjusted group II (the control group...
Purpose To compare the postoperative efficacy, safety, and higher-order-aberrations (HOAs) between transepithelial photorefractive keratectomy (PRK) and alcohol-assisted PRK in contralateral eyes. Setting Private clinic, Utrecht, The Netherlands. Design Comparative case series. Methods Consecutive patients were randomized to have transepithelial PRK in 1 eye and alcohol-assisted PRK in the contralateral eye. In both eyes, aspheric treatments were planned with Custom Ablation Manager software and...