Nonglutaraldehyde treated porcine pericardium with good biocompatibility, reduced calcification and improved Anti-coagulation for bioprosthetic heart valve applications

Heart valve diseases, such as valve stenosis and regurgitation, are one of the important reasons for the high morbidity and mortality of cardiovascular diseases, and the heart valve replacement has become the optimal option for severe heart valve disease treatment. With the development of transcatheter heart valve replacement technology and aging population, the usage of bioprosthetic heart valves (BHVs) has been largely expanded. As the golden...