Review paper

The Current State of Oncolytic Herpes Simplex Virus for Glioblastoma Treatment

Volume: Volume 10, Pages: 1 - 27
Published: Feb 1, 2021
Abstract
Glioblastoma (GBM) is a lethal primary malignant brain tumor with no current effective treatments. The recent emergence of immuno-virotherapy and FDA approval of T-VEC have generated a great expectation towards oncolytic herpes simplex viruses (oHSVs) as a promising treatment option for GBM. Since the generation and testing of the first genetically engineered oHSV in glioma in the early 1990s, oHSV-based therapies have shown a long way of great...
Paper Details
Title
The Current State of Oncolytic Herpes Simplex Virus for Glioblastoma Treatment
Published Date
Feb 1, 2021
Volume
Volume 10
Pages
1 - 27
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