Coronavirus

Intensive care medicine

2019-20 coronavirus outbreak

Engineering

Public health

Betacoronavirus

Global health

Virology

Middle East respiratory syndrome

Telecommunications

Computer science

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Outbreak

Environmental health

Coronavirus disease 2019 (COVID-19)

Immunology

Atypical pneumonia

Middle East respiratory syndrome coronavirus

Infectious disease (medical specialty)

Internal medicine

Coronavirus Infections

Medicine

Transmission (telecommunications)

Pneumonia

Pandemic

Disease

Human health

Electrical engineering

Pathology

Frontiers in Cellular and Infection Microbiology

In late December 2019, a vtiral pneumonia with an unknown agent was reported in Wuhan, China. A novel coronavirus was identified as the causative agent. Because of the human-to-human transmission and rapid spread; coronavirus disease 2019 (COVID-19) has rapidly increased to an epidemic scale and poses a severe threat to human health; it has been declared a public health emergency of international concern (PHEIC) by the World Health Organization (WHO). This review aims to summarize the recent research progress of COVID-19 molecular features and immunopathogenesis to provide a reference for further research in prevention and treatment of SARS coronavirus2 (SARS-CoV-2) infection based on the knowledge from researches on SARS-CoV and Middle East respiratory syndrome-related coronavirus (MERS-CoV).

COVID-19: Molecular and Cellular Response