Frontiers in Cellular and Infection Microbiology
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#1Johanna Reinold (University of Duisburg-Essen)H-Index: 1
#2Farnoush Farahpour (University of Duisburg-Essen)H-Index: 7
Last. Oliver Witzke (University of Duisburg-Essen)H-Index: 55
view all 12 authors...
The gut microbiota contributes to maintaining human health and regulating immune responses. Severe COVID-19 illness is associated with a dysregulated pro-inflammatory immune response. The effect of SARS-CoV-2 on altering the gut microbiome and the relevance of the gut microbiome on COVID-19 severity needs to be clarified. In this prospective study, we analysed the gut microbiome of 212 patients of a tertiary care hospital (117 patients infected with SARS-CoV-2 and 95 SARS-CoV-2 negative patients...
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#1Susmita Das (WSU: Wayne State University)
#2Sukhvinder Singh (WSU: Wayne State University)H-Index: 8
Last. Ashok Kumar (WSU: Wayne State University)H-Index: 29
view all 3 authors...
Coagulase-negative staphylococci (CoNS), including Staphylococcus (S) epidermidis are responsible for ~70% of all post-surgical endophthalmitis, a potentially blinding eye infection. However, the pathobiology of CoNS endophthalmitis is limited to epidemiological and clinical case studies with few experimental studies. Here, we report both in vitro and in vivo models to study the pathobiology of S. epidermidis endophthalmitis in mice. We found that S. epidermidis is rapidly cleared from mouse eye...
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#1Xingqun Cheng (SCU: Sichuan University)H-Index: 7
#2Xuedong Zhou (SCU: Sichuan University)H-Index: 62
Last. Xin Xu (SCU: Sichuan University)H-Index: 32
view all 4 authors...
Osteomicrobiology is a new research field in which the aim is to explore the role of microbiota in bone homeostasis. The alveolar bone is that part of the maxilla and mandible that supports the teeth. It is now evident that naturally occurring alveolar bone loss is considerably stunted in germ-free mice compared with specific-pathogen-free mice. Recently, the roles of oral microbiota in modulating host defense systems and alveolar bone homeostasis have attracted increasing attention. Moreover, t...
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#1Jing Gao (Fudan University)
Last. Chunmei Ying (Fudan University)H-Index: 3
view all 6 authors...
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#1Birgit Fritz (Life Sciences Institute)H-Index: 2
#2Edita Paschko (Life Sciences Institute)
Last. Markus Egert (Life Sciences Institute)H-Index: 21
view all 7 authors...
Slit lamps are routinely used to examine large numbers of patients every day due to high throughput. Previous, cultivation-based results suggested slit lamps to be contaminated with bacteria, mostly coagulase-negative staphylococci, followed by micrococci, bacilli, but also Staphylococcus aureus. Our study aimed at obtaining a much more comprehensive, cultivation-independent view of the slit lamp bacteriota and its hygienic relevance, as regularly touched surfaces usually represent fomites, part...
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#1Zeming Liu (HUST: Huazhong University of Science and Technology)H-Index: 15
#2Di Hu (WHU: Wuhan University)H-Index: 4
Last. Meng Wu (WHU: Wuhan University)H-Index: 2
view all 12 authors...
Background: Coronavirus disease 2019 (COVID-19) has evolved into a pandemic. We hypothesized that biochemical indicators of liver function may help determine the prognosis of COVID-19 patients. Methods: Patient information was collected from the Wuhan-Leishenshan hospital. Logistic and Cox regression analyses, Kaplan-Meier curves, and Curve fitting were used to determine the correlation between elevated levels of aspartate transaminase (AST), alanine transaminase (ALT), and AST/ALT and severity ...
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