Harnessing Tumor Necrosis Factor Alpha to Achieve Effective Cancer Immunotherapy
Abstract
Tumor necrosis factor alpha (TNFα) is a pleiotropic cytokine known to have contradictory roles in oncoimmunology. Indeed, TNFα has a central role in the onset of the immune response, inducing both activation and the effector function of macrophages, dendritic cells, natural killer (NK) cells, and B and T lymphocytes. Within the tumor microenvironment, however, TNFα is one of the main mediators of cancer-related inflammation. It is involved in...
Paper Details
Title
Harnessing Tumor Necrosis Factor Alpha to Achieve Effective Cancer Immunotherapy
Published Date
Feb 2, 2021
Journal
Volume
13
Issue
3
Pages
564 - 564
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