Quaternary polymethacrylate−magnesium aluminum silicate film formers: Stability studies for tablet coatings

The objective of this work was to investigate the long-term stability of quaternary polymethacrylate-magnesium aluminum silicate (QPM-MAS) nanocomposite film-coated tablets compared to that of QPM-coated tablets. QPM- and QPM-MAS-coated tablets prepared without or with a curing process at 60 °C for 12 h were stored without packaging under ambient (26 ± 2 °C, 50% relative humidity (RH)) and accelerated (45 ± 1 °C, 75% RH) conditions. The outer...