Altered regional grey matter volume and appetite-related hormone levels in adolescent obesity with or without binge-eating disorder

Binge eating disorder (BED) is characterized by frequent and persistent overeating episodes of binge eating without compensatory behaviors. The aim was to evaluate regional gray matter volume (GMV) abnormalities and appetite-regulating hormone levels (NPY and Leptin) in obese subjects either with or without BED compared to healthy controls (HC). Twenty-six obese patients with BED, 25 obese patients without BED and 27 healthy subjects as an...