Light up multiple protein dimers on cell surface based on proximity-induced fluorescence activation of DNA-templated sliver nanoclusters
Abstract
Efficient and multiple analysis of receptor protein dimers is highly necessary, due to their important role in the occurrence and development of cancer. Herein, we report a turn-on strategy to visualize human epidermal growth factor receptor (HER) dimers on cell surfaces. By taking advantages of specific aptamer recognition and proximity-induced fluorescence activation of DNA-templated sliver nanoclusters (DNA/AgNCs) by guanine (G)-rich...
Paper Details
Title
Light up multiple protein dimers on cell surface based on proximity-induced fluorescence activation of DNA-templated sliver nanoclusters
Published Date
May 1, 2021
Volume
179
Pages
113064 - 113064
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