Biosensors and Bioelectronics
Papers 10,000
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#1Hyeon Ji Park (Ajou University)H-Index: 2
#2Cheulhee Jung (Korea University)H-Index: 22
Last. Tae Hyeon Yoo (Ajou University)H-Index: 17
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Abstract null null Ribonucleic acids (RNAs) provide valuable information for biological systems and act as important indicators of disease states. RNAs are diverse in size and structure, and various strategies have been proposed for the detection of nucleic acids; however, developing them into point-of-care (POC) tests has been challenging as most of them consist of complex time-consuming steps. Here, we propose a strategy to assay RNAs using a hairpin-loop (HP) converter and proximity proteolys...
#1Seung Jun Lee (GNU: Gyeongsang National University)H-Index: 21
#2Hyeyeon Lee (GNU: Gyeongsang National University)H-Index: 3
Last. Myong Yong Choi (GNU: Gyeongsang National University)H-Index: 30
view all 9 authors...
Abstract null null Herein, gold nanoparticles (Au NPs) were synthesized by pulsed laser ablation (PLAL) in a mixed-phase solvent of acetonitrile and water. The size of Au NPs and the number of graphitic carbon (GC) layers were controlled by varying the ratio of the solvent mixture. The surface-enhanced Raman scattering (SERS) of the Au NPs was investigated using 10−3 M 4-aminobenzenethiol (4-ABT) and 10−4 M 4-nitrobenzenethiol (4-NBT) as probe molecules. The SERS activity strongly depended on th...
#1Abdelmonaim AzzouzH-Index: 15
#2Lamia HejjiH-Index: 2
Last. Wei Zhang (Zhengzhou University)H-Index: 4
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Surface plasmon resonance approach is a highly useful option to offer optical and label-free detection of target bioanalytes with numerous advantages (e.g., low-cost fabrication, appreciable sensitivity, label-free detection, and outstanding accuracy). As such, it allows early diagnosis of cancer biomarkers to monitor tumor progression and to prevent the recurrence of oncogenic tumors. This work highlights the recent progress in SPR biosensing technology for the diagnosis of various cancer types...
#1Gretchen Tibbits (WSU: Washington State University)H-Index: 1
#2Abdelrhman Mohamed (WSU: Washington State University)H-Index: 8
Last. Haluk Beyenal (WSU: Washington State University)H-Index: 57
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Conventional methods for testing antibiotic susceptibility rely on bacterial growth on agar plates (diffusion assays) or in liquid culture (microdilution assays). These time-consuming assays use population growth as a proxy for cellular respiration. Herein we propose to use mediated extracellular electron transfer as a rapid and direct method to classify antibiotic-susceptible and -resistant bacteria. We tested antibiotics with diverse mechanisms of action (ciprofloxacin, imipenem, oxacillin, or...
#1Brij Mohan (HIT: Harbin Institute of Technology)H-Index: 5
#2Sandeep Kumar (HIT: Harbin Institute of Technology)H-Index: 4
Last. Peng Ren (HIT: Harbin Institute of Technology)H-Index: 2
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Abstract null null In the health domain, a major challenge is the detection of diseases using rapid and cost-effective techniques. Most of the existing cancer detection methods show poor sensitivity and selectivity and are time consuming with high cost. To overcome this challenge, we analyzed porous fabricated metal-organic frameworks (MOFs) that have better structures and porosities for enhanced biomarker sensing. Here, we summarize the use of fabricated MOF luminescence and electrochemical sen...
#1Hejie Zheng (Henan University)H-Index: 5
#2Si Zhang (Henan University)H-Index: 7
Last. Danny K.Y. Wong (Macquarie University)H-Index: 28
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Abstract null null A major aspect of this work is the synergistic application of a poly(diphenylbutadiene)-BiOBr composite and a gold nanoparticle-linked CeO2 octahedron to develop a photoelectrochemical aptasensor with an easily measurable detection signal change. Specifically, poly(diphenylbutadiene) nanofiber-immobilised BiOBr flower-like microspheres were developed as a hybrid material with a heterojunction that facilitates high visible light absorption and efficient photo-generated charge s...
#1Quynh Anh Phan (NU: Northeastern University)
#2Linh B. Truong (NU: Northeastern University)
Last. Ebrahim Mostafavi (SU: Stanford University)H-Index: 18
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Abstract null null CRISPR diagnostics (CRISPR-Dx) offer a wide range of enhancements compared to traditional nanobiosensors by taking advantage of the excellent trans-cleavage activity of the CRISPR/Cas systems. However, the single-stranded DNA/RNA reporters of the current CRISPR-Dx suffer from poor stability and limited sensitivity, which make their application in complex biological environments difficult. In comparison, nanomaterials, especially metal nanoparticles, exhibits robust stability a...
#1Santheraleka Ramanathan (KUKUM: Universiti Malaysia Perlis)H-Index: 10
#2Subash C. B. Gopinath (KUKUM: Universiti Malaysia Perlis)H-Index: 52
Last. Prabakaran Poopalan (KUKUM: Universiti Malaysia Perlis)H-Index: 19
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Abstract null null In an aim of developing portable biosensor for SARS-CoV-2 pandemic, which facilitates the point-of-care aptasensing, a strategy using 10 μm gap-sized gold interdigitated electrode (AuIDE) is presented. The silane-modified AuIDE surface was deposited with ∼20 nm diamond and enhanced the detection of SARS-CoV-2 nucleocapsid protein (NCP). The characteristics of chemically modified diamond were evidenced by structural analyses, revealing the cubic crystalline nature at (220) and ...
#1Zifan Tang (PSU: Pennsylvania State University)H-Index: 10
#2Reza Nouri (PSU: Pennsylvania State University)H-Index: 5
Last. Weihua Guan (PSU: Pennsylvania State University)H-Index: 21
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Abstract null null The current pandemic of COVID-19 caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2) has raised significant public health concerns. Rapid and accurate testing of SARS-CoV-2 is urgently needed for early detection and control of the disease spread. Here, we present an RT-LAMP coupled glass nanopore digital counting method for rapid detection of SARS-CoV-2. We validated and compared two one-pot RT-LAMP assays targeting nucleocapsid (N) and envelop (E) genes. Th...
#1Marc Parrilla (University of Antwerp)H-Index: 15
#2Andres Vanhooydonck (University of Antwerp)H-Index: 1
Last. Karolien De Wael (University of Antwerp)H-Index: 27
view all 4 authors...
Wearable electrochemical sensors are driven by the user-friendly capability of on-site detection of key biomarkers for health management. Despite the advances in biomolecule monitoring such as glucose, still, several unmet clinical challenges need to be addressed. For example, patients suffering from phenylketonuria (PKU) should be able to monitor their phenylalanine (PHE) level in a rapid, decentralized, and affordable manner to avoid high levels of PHE in the body which can lead to a profound ...
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