Evaluation of the predictive capability of PETAL tool: a retrospective study on potential tyrosine kinases drug resistance targets

An ever-increasing number of tools and databases offers pieces of evidence and knowledge about gene function annotations, protein interactions, and experimentally validated biological pathways. These resources represent an excellent and essential instrument to facilitate pathway analysis. Among them, particular attention should be given to the one capable of finding alternative pathways or cross-talks events and potential drug target candidates....