Trabecular complexity as an early marker of cardiac involvement in Fabry disease

Fabry cardiomyopathy is characterized by glycosphingolipid storage and increased myocardial trabeculation has also been demonstrated. This study aimed to explore by cardiac magnetic resonance whether myocardial trabecular complexity, quantified by endocardial border fractal analysis, tracks phenotype evolution in Fabry cardiomyopathy.Study population included 20 healthy controls (12 males, age 32±9) and 45 Fabry patients divided into three...