Antonia Camporeale
Catholic University of the Sacred Heart
Subclinical infectionInternal medicinePathologyMagnetic resonance imagingRenal functionCardiologyPR intervalIschemic cardiomyopathyBiopsyLeft ventricular hypertrophyImplantable cardioverter-defibrillatorFabry diseaseCardiac amyloidosisHeart failureCardiomyopathyVentricleAtrial fibrillationAtrium (heart)Right ventricular hypertrophyEnzyme replacement therapyElectrocardiographyHypertrophic cardiomyopathyRight bundle branch blockDifferential diagnosisMyocarditisPopulationLeft atrialCardiac magnetic resonancePlatelet reactivityIn patientRight ventricular cardiomyopathyStrokeDiastoleMedicineEjection fraction
Publications 41
Abstract null Objectives null To elaborate an ECG-based nomogram estimating the probability to detect cardiac involvement by cardiac magnetic resonance (CMR) in Fabry Disease (FD). null Methods null 119 FD patients and 26 healthy controls underwent ECG and CMR. Test (n = 88, 60%) and validation cohorts (n = 57, 40%) were randomly derived. Cardiac involvement was defined as the presence of low myocardial T1 value, a CMR-surrogate of myocardial glycosphingolipid storage. ECG changes associated wit...
#2L TondiH-Index: 1
Last. Kelvin Chow (Siemens)H-Index: 19
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#1Veronica Melita (UCSC: Catholic University of the Sacred Heart)H-Index: 3
#2Lara TondiH-Index: 1
Last. Silvia PicaH-Index: 12
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#1Rosa Lillo (UCSC: Catholic University of the Sacred Heart)H-Index: 1
#1Rosa LilloH-Index: 1
Last. Filippo Crea (UCSC: Catholic University of the Sacred Heart)H-Index: 103
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Abstract Background 2D speckle tracking echocardiography (2DSTE) is superior to standard echocardiography in the assessment of subtle right ventricle (RV) systolic dysfunction. In this study we aimed to: 1) test the hypothesis that 2DSTE may unveil subtle RV systolic dysfunction in patients with Fabry disease; 2) investigate whether the physiologic difference between the 3-segment (RV-FWS) and the 6-segment (RV-GLS) RV strain (∆RV strain) is preserved in Fabry patients. Methods and results Stand...
#1Maurizio PieroniH-Index: 32
#2James C. Moon (UCL: University College London)H-Index: 76
Last. Mehdi NamdarH-Index: 26
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Fabry disease (FD) is a rare X-linked inherited lysosomal storage disorder caused by deficient α-galactosidase A activity that leads to an accumulation of globotriasylceramide (Gb3) in affected tissues, including the heart. Cardiovascular involvement usually manifests as left ventricular hypertrophy, myocardial fibrosis, heart failure, and arrhythmias, which limit quality of life and represent the most common causes of death. Following the introduction of enzyme replacement therapy, early diagno...
6 CitationsSource
#1Giovanni Vitale (UNIBO: University of Bologna)H-Index: 13
#2Raffaello Ditaranto (UNIBO: University of Bologna)H-Index: 2
Last. Elena Biagini (UNIBO: University of Bologna)H-Index: 40
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Objectives To evaluate the role of the ECG in the differential diagnosis between Anderson-Fabry disease (AFD) and hypertrophic cardiomyopathy (HCM). Methods In this multicentre retrospective study, 111 AFD patients with left ventricular hypertrophy were compared with 111 patients with HCM, matched for sex, age and maximal wall thickness by propensity score. Independent ECG predictors of AFD were identified by multivariate analysis, and a multiparametric ECG score-based algorithm for differential...
#1Francesca GrazianiH-Index: 12
#2Rosa Lillo (UCSC: Catholic University of the Sacred Heart)H-Index: 1
Last. Filippo Crea (UCSC: Catholic University of the Sacred Heart)H-Index: 103
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AIMS In Fabry cardiomyopathy, left ventricular outflow tract obstruction mimicking hypertrophic cardiomyopathy is a very rare finding, with few cases reported and successfully treated with cardiac surgery. In our population of patients with Fabry disease and severe left ventricular hypertrophy (LVH) at the time of diagnosis, we observed an evolution towards a midventricular obstructive phenotype. METHODS AND RESULTS We present a case series of three classically affected Fabry male patients with ...
#1Antonia CamporealeH-Index: 7
#2Francesco Moroni (UniSR: Vita-Salute San Raffaele University)H-Index: 14
Last. Massimo LombardiH-Index: 61
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AIMS Fabry cardiomyopathy is characterized by glycosphingolipid storage and increased myocardial trabeculation has also been demonstrated. This study aimed to explore by cardiac magnetic resonance whether myocardial trabecular complexity, quantified by endocardial border fractal analysis, tracks phenotype evolution in Fabry cardiomyopathy. METHODS AND RESULTS Study population included 20 healthy controls (12 males, age 32±9) and 45 Fabry patients divided into three groups: 15 left ventricular hy...
#1Stefano Figliozzi (St Thomas' Hospital)H-Index: 6
#2Antonia CamporealeH-Index: 7
Last. Massimo LombardiH-Index: 61
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1 CitationsSource