Original paper
The effects of meldonium on the acute ischemia/reperfusion liver injury in rats
Abstract
Acute ischemia/reperfusion (I/R) liver injury is a clinical condition challenging to treat. Meldonium is an anti-ischemic agent that shifts energy production from fatty acid oxidation to less oxygen-consuming glycolysis. Thus, we investigated the effects of a 4-week meldonium pre-treatment (300 mg/kg b.m./day) on the acute I/R liver injury in Wistar strain male rats. Our results showed that meldonium ameliorates I/R-induced liver inflammation...
Paper Details
Title
The effects of meldonium on the acute ischemia/reperfusion liver injury in rats
Published Date
Jan 14, 2021
Journal
Volume
11
Issue
1
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Notes
History