Review paper
TRIM proteins in lung cancer: Mechanisms, biomarkers and therapeutic targets
Abstract
The tripartite motif (TRIM) family is defined by the presence of a Really Interesting New Gene (RING) domain, one or two B-box motifs and a coiled-coil region. TRIM proteins play key roles in many biological processes, including innate immunity, tumorigenesis, cell differentiation and ontogenetic development. Alterations in TRIM gene and protein levels frequently emerge in a wide range of tumors and affect tumor progression. As canonical E3...
Paper Details
Title
TRIM proteins in lung cancer: Mechanisms, biomarkers and therapeutic targets
Published Date
Mar 1, 2021
Journal
Volume
268
Pages
118985 - 118985
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