doi.org/10.1016/j.cell.2020.12.020
Original paper

The Rise of Molecular Glues

Stuart L. Schreiber
124
Cell64.50
Volume: 184, Issue: 1, Pages: 3 - 9
Published: Jan 1, 2021
Abstract
2021 marks the 30th anniversary of the revelation that cyclosporin A and FK506 act in a way previously not seen—as “molecular glues” that induce neo-protein–protein associations. As a torrent of new molecular-glue probes and medicines are fueling interest in this field, I explore the arc of this story. 2021 marks the 30th anniversary of the revelation that cyclosporin A and FK506 act in a way previously not seen—as “molecular glues” that induce...
Paper Fields
Paper Details
Title
The Rise of Molecular Glues
DOI
doi.org/10.1016/j.cell.2020.12.020
Published Date
Jan 1, 2021
Journal
Cell
Volume
184
Issue
1
Pages
3 - 9
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