Sol–Gel Nanocomposite Coatings for Preventing Biofilm Formation on Contact Lens Cases

Purpose: To evaluate the efficacy of a nanosilver-based sol–gel coating in preventing biofilm formation on contact lens cases. Methods: An organic–inorganic hybrid silica–zirconia sol formulation with immobilized silver nanoparticles was deposited on contact lens case coupons. The coated and uncoated coupons were subjected to biofilm formation to Gram-negative and Gram-positive keratitis isolates and ATCC strains using a standard protocol. The...