Association of Heavy Drinking With Deviant Fiber Tract Development in Frontal Brain Systems in Adolescents

Importance

Maturation of white matter fiber systems subserves cognitive, behavioral, emotional, and motor development during adolescence. Hazardous drinking during this active neurodevelopmental period may alter the trajectory of white matter microstructural development, potentially increasing risk for developing alcohol-related dysfunction and alcohol use disorder in adulthood.

Objective

To identify disrupted adolescent...