Importance null Only one-third of patients with complex psychiatric disorders engage in specialty mental health care, and only one-tenth receive adequate treatment in primary care. Scalable approaches are critically needed to improve access to effective mental health treatments in underserved primary care settings. null Objective null To compare 2 clinic-to-clinic interactive video approaches to delivering evidence-based mental health treatments to patients in primary care clinics. null Design, ...
Importance null The COVID-19 pandemic has raised considerable concerns about increased risk for suicidal behavior among US military veterans, who already had elevated rates of suicide before the pandemic. null Objective null To examine longitudinal changes in suicidal behavior from before the COVID-19 pandemic to nearly 10 months into the pandemic and identify risk factors and COVID-related variables associated with new-onset suicide ideation (SI). null Design, setting, and participants null Thi...
#1Stefan Leucht('KCL': King's College London)H-Index: 1
#2Sofia Bauer(LMU: Ludwig Maximilian University of Munich)
Last. John M. Davis(UIC: University of Illinois at Chicago)H-Index: 1
view all 8 authors...
Importance null The doses of antipsychotic drugs needed for relapse prevention in schizophrenia is a debated issue. null Objective null To examine dose-response findings in a meta-analysis of randomized clinical trials. null Data Sources null Studies were identified through the Cochrane Schizophrenia Group’s Study-Based Register of Trials (March 9, 2020), PubMed (January 1, 2021), and previous reviews. First authors and/or pharmaceutical companies were contacted for additional information. null ...
Importance null Anxiety is common among patients with coronary heart disease (CHD) and is associated with worse health outcomes; however, effective treatment for anxiety in patients with CHD is uncertain. null Objective null To determine whether exercise and escitalopram are better than placebo in reducing symptoms of anxiety as measured by the Hospital Anxiety and Depression-Anxiety Subscale (HADS-A) and in improving CHD risk biomarkers. null Design, Setting, and Participants null This randomiz...
#2Jackson G. Thorp(QIMR: QIMR Berghofer Medical Research Institute)H-Index: 2
Last. Nicholas G. Martin(QIMR: QIMR Berghofer Medical Research Institute)H-Index: 205
view all 13 authors...
Importance null Genetic studies with broad definitions of depression may not capture genetic risk specific to major depressive disorder (MDD), raising questions about how depression should be operationalized in future genetic studies. null Objective null To use a large, well-phenotyped single study of MDD to investigate how different definitions of depression used in genetic studies are associated with estimation of MDD and phenotypes of MDD, using polygenic risk scores (PRSs). null Design, Sett...
Importance null Schizophrenia is a clinically heterogeneous disorder. It is currently unclear how variability in symptom dimensions and cognitive ability is associated with genetic liability for schizophrenia. null Objective null To determine whether phenotypic dimensions within schizophrenia are associated with genetic liability to schizophrenia, other neuropsychiatric disorders, and intelligence. null Design, Setting, and Participants null In a genetic association study, 3 cross-sectional samp...