Original paper
Celastrol attenuates ischemia/reperfusion-mediated memory dysfunction by downregulating AK005401/MAP3K12
Abstract
Oxidative stress induces mitochondrial dysfunction, causing memory loss. Long noncoding RNAs influence mitochondrial function and suppress oxidative stress by regulating target protein expression and gene transcription. Celastrol, a natural antioxidant extracted from Tripterygium wilfordii Hook F. (“Thunder of God Vine”), effectively alleviates oxidative stress-mediated tissue injury. In the present study, we examined the effects of celastrol on...
Paper Details
Title
Celastrol attenuates ischemia/reperfusion-mediated memory dysfunction by downregulating AK005401/MAP3K12
Published Date
Feb 1, 2021
Journal
Volume
82
Pages
153441 - 153441
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Notes
History