Hyponatremia and other electrolyte abnormalities in patients receiving immune checkpoint inhibitors

Hyponatremia due to endocrinopathies such as adrenal insufficiency and hypothyroidism has been reported in patients receiving immune checkpoint inhibitors (ICIs). We determined the risk and predictors of hyponatremia and other electrolyte abnormalities in a 'real-world' sample of patients receiving ICIs to treat advanced malignancies.This was a retrospective observational study of all patients who received ICIs from a single cancer center...