Adipose tissue is a critical regulator of osteoarthritis

Abstract
Osteoarthritis (OA), the leading cause of pain and disability worldwide, disproportionally affects individuals with obesity. The mechanisms by which obesity leads to the onset and progression of OA are unclear due to the complex interactions among the metabolic, biomechanical, and inflammatory factors that accompany increased adiposity. We used a murine preclinical model of lipodystrophy (LD) to examine the direct contribution of adipose tissue...
Paper Details
Title
Adipose tissue is a critical regulator of osteoarthritis
Published Date
Dec 21, 2020
Volume
118
Issue
1
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