Small Animal IMRT Using 3D-Printed Compensators

Purpose Preclinical radiation replicating clinical intensity modulated radiation therapy (IMRT) techniques can provide data translatable to clinical practice. For this work, treatment plans were created for oxygen-guided dose-painting in small animals using inverse-planned IMRT. Spatially varying beam intensities were achieved using 3-dimensional (3D)-printed compensators. Methods and Materials Optimized beam fluence from arbitrary gantry angles...