Desynchronized Functional Activities Between Brain White and Gray Matter in Major Depression Disorder

Background Alterations in gray matter (GM) have been recognized as playing an important role in the neurobiological mechanism underlying major depressive disorder (MDD) and antidepressant responses. However, little is known about white matter (WM) connectivity in MDD, leaving an incomplete understanding of the pathophysiology of the disorder. Purpose To examine the functional connectivity (FC) of WM, GM, and WM‐GM in MDD patients and explore the...