Adverse effect

Physical therapy

Mindfulness

Macroeconomics

Internal medicine

Randomized controlled trial

Mindfulness-based stress reduction

Economics

Medicine

Migraine

Nursing

Quality of life (healthcare)

Clinical psychology

Depression (economics)

JAMA Internal Medicine

Migraine is the second leading cause of disability worldwide. Most patients with migraine discontinue medications due to inefficacy or adverse effects. Mindfulness-based stress reduction (MBSR) may provide benefit.To determine if MBSR improves migraine outcomes and affective/cognitive processes compared with headache education.This randomized clinical trial of MBSR vs headache education included 89 adults who experienced between 4 and 20 migraine days per month. There was blinding of participants (to active vs comparator group assignments) and principal investigators/data analysts (to group assignment).Participants underwent MBSR (standardized training in mindfulness/yoga) or headache education (migraine information) delivered in groups that met for 2 hours each week for 8 weeks.The primary outcome was change in migraine day frequency (baseline to 12 weeks). Secondary outcomes were changes in disability, quality of life, self-efficacy, pain catastrophizing, depression scores, and experimentally induced pain i...

Effectiveness of Mindfulness Meditation vs Headache Education for Adults With Migraine