Induction and Analysis of Oxidative Stress in <em>Sleeping Beauty</em> Transposon-Transfected Human Retinal Pigment Epithelial Cells
Abstract
Oxidative stress plays a critical role in several degenerative diseases, including age-related macular degeneration (AMD), a pathology that affects ~30 million patients worldwide. It leads to a decrease in retinal pigment epithelium (RPE)-synthesized neuroprotective factors, e.g., pigment epithelium-derived factor (PEDF) and granulocyte-macrophage colony-stimulating factor (GM-CSF), followed by the loss of RPE cells, and eventually photoreceptor...
Paper Details
Title
Induction and Analysis of Oxidative Stress in <em>Sleeping Beauty</em> Transposon-Transfected Human Retinal Pigment Epithelial Cells
Published Date
Dec 11, 2020
Issue
166
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