Defining the role of the Alzheimer disease risk factor CD2AP in brain vascular function
Abstract
Background Brain hypoperfusion is the earliest change observed in Alzheimer’s Disease (AD) brains. Degeneration of the brain vasculature, that includes cerebral amyloid pathology, white matter hyperintensities and cortical infracts, isomnipresent in AD, and predicts the progression of cognitive decline in AD patients. CD2‐associated protein (CD2AP) functions as scaffolding protein for cytoskeletal remodeling, membrane trafficking during...
Paper Details
Title
Defining the role of the Alzheimer disease risk factor CD2AP in brain vascular function
Published Date
Dec 1, 2020
Journal
Volume
16
Issue
S3
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