Oligomeric amyloid‐beta 1–42 inhibits antigen presentation

Background Beyond microglia, the involvement of other immune cell types and immune functions in Alzheimer’s disease (AD) is not well understood. Here, we investigated the potential immunomodulatory properties in vivo and in vitro of oligomeric species of beta‐amyloid‐peptide (Aβ) on microglia and other putative antigen presenting cells (APCs). Methods We used multicolour flow‐cytometry, confocal microscopy and MSD biochemical analysis to...