Maria Teresa Ferretti
University of Zurich
TransgeneInternal medicinePathologyPrecision medicineNeuroscienceAcquired immune systemImmunologyInflammationSex characteristicsDiseaseMEDLINEMicrogliaAmyloidosisHippocampusAmyloid precursor proteinAlzheimer's diseaseClinical trialClinical psychologyMedicineCohortIntracellularBiologyAmyloidImmune system
43Publications
18H-index
1,121Citations
Publications 41
Newest
#1Christoph Gericke (UZH: University of Zurich)H-Index: 1
#2Tunahan Kirabali (UZH: University of Zurich)H-Index: 3
Last. Valerie Treyer (UZH: University of Zurich)H-Index: 39
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Fast and minimally invasive approaches for early, preclinical diagnosis of neurodegenerative Alzheimer’s disease (AD) are highly anticipated. Evidence of adaptive immune cells responding to cerebral β-amyloidosis, one of the pathological hallmarks of AD, has raised the question of whether immune markers could be used as proxies for β-amyloid accumulation in the brain. Here, we deploy multidimensional mass cytometry combined with unbiased machine learning techniques to immunophenotype peripheral ...
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#1Annemarie Schumacher Dimech (University of Lucerne)
Last. Antonella Santuccione Chadha (Biogen Idec)H-Index: 3
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#1Katrin RauenH-Index: 4
#2Claudia B Späni (NU: Northwestern University)H-Index: 1
Last. Nikolaus Plesnila (LMU: Ludwig Maximilian University of Munich)H-Index: 55
view all 10 authors...
Traumatic brain injury (TBI) is the leading cause of disability in the working population and becomes increasingly prevalent in the elderly. Thus, TBI is a major global health burden. However, age- and sex-related long-term outcome regarding patient's health-related quality of life (HRQoL) is yet not clarified. In this cross-sectional study, we present age- and sex-related demographics and HRQoL up to 10 years after TBI using the Quality of Life after Brain Injury (QOLIBRI) instrument. The QOLIB...
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#1Alberto FerrariH-Index: 2
#2Enrico Santus (Bayer)H-Index: 16
Last. Alfonso Valencia (Barcelona Supercomputing Center)H-Index: 115
view all 9 authors...
Targeted contact-tracing through mobile phone apps has been proposed as an instrument to help contain the spread of COVID-19 and manage the lifting of nation-wide lock-downs currently in place in USA and Europe. However, there is an ongoing debate on its potential efficacy, especially in light of region-specific demographics. We built an expanded SIR model of COVID-19 epidemics that accounts for region-specific population densities, and we used it to test the impact of a contact-tracing app in a...
5 CitationsSource
#1Carla Abdelnour (ISCIII: Carlos III Health Institute)H-Index: 14
#2Sergi Valero (ISCIII: Carlos III Health Institute)H-Index: 4
Last. Mercè Boada (ISCIII: Carlos III Health Institute)H-Index: 54
view all 16 authors...
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#1Christoph Gericke (UZH: University of Zurich)H-Index: 1
#1Christoph Gericke (UZH: University of Zurich)H-Index: 1
Last. Maria Teresa Ferretti (UZH: University of Zurich)H-Index: 18
view all 5 authors...
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#1Christoph Gericke (UZH: University of Zurich)H-Index: 1
#1Christoph Gericke (UZH: University of Zurich)H-Index: 1
Last. Maria Teresa Ferretti (UZH: University of Zurich)H-Index: 18
view all 5 authors...
Genetic, clinical, biochemical and histochemical data indicate a crucial involvement of inflammation in Alzheimer's disease (AD), but harnessing the immune system to cure or prevent AD has so far proven difficult. Clarifying the cellular heterogeneity and signaling pathways associated with the presence of the AD hallmarks beta-amyloid and tau in the brain, would help to identify potential targets for therapy. While much attention has been so far devoted to microglia and their homeostatic phagocy...
1 CitationsSource
#1Alberto FerrariH-Index: 2
#2Enrico Santus (Bayer)H-Index: 16
Last. Alfonso Valencia (Barcelona Supercomputing Center)H-Index: 115
view all 9 authors...
Targeted contact-tracing through mobile phone apps has been proposed as an instrument to help contain the spread of COVID-19 and manage the lifting of nation-wide lockdowns currently in place in USA and Europe. However, there is an ongoing debate on its potential efficacy, especially in the light of region-specific demographics. We built an expanded SIR model of COVID-19 epidemics that accounts for region-specific population densities, and we used it to test the impact of a contact-tracing app i...
3 CitationsSource
#1Evelyne Bischof (SJTU: Shanghai Jiao Tong University)H-Index: 1
#2Guoting Chen (Tongji University)H-Index: 1
Last. Maria Teresa FerrettiH-Index: 18
view all 3 authors...
The change in diagnostic criteria for COVID-19 diagnosis in Hubei province caused a shift in the numbers of total cases overnight. The aim of this article is to explain the rationale for the choice of the new criteria and the meaning of the new data, from the perspective of the authors based in Shanghai, China, struck by the level of panic and emotional distress in many people that has been generated by the new data.
6 CitationsSource
#1Maria Teresa Ferretti (UZH: University of Zurich)H-Index: 18
#2J. Martinkova (Charles University in Prague)H-Index: 1
Last. Reinhold Schmidt (University of Graz)H-Index: 99
view all 12 authors...
Alzheimer's disease (AD) is characterized by high heterogeneity in disease manifestation, progression and risk factors. High phenotypic variability is currently regarded as one of the biggest hurdles in early diagnosis and in the design of clinical trials; there is therefore great interest in identifying factors driving variability and that can be used for patient stratification. In addition to genetic and life-style factors, the individual's sex and gender is emerging as a crucial driver of phe...
18 CitationsSource