Dectin‐1–mediated suppression of RANKL‐induced osteoclastogenesis by glucan from baker's yeast
Abstract
Immunoreceptors expressed on osteoclast precursor cells modify osteoclast differentiation and bone resorption activity. Dectin-1 is a lectin receptor of β-glucan and is specifically expressed in osteoclast precursor cells. In this study, we evaluated the bioactivity of β-glucan on receptor activator of nuclear factor-kappa B ligand (RANKL)-induced osteoclastogenesis and observed that glucan from baker's yeast inhibited this process in mouse bone...
Paper Details
Title
Dectin‐1–mediated suppression of RANKL‐induced osteoclastogenesis by glucan from baker's yeast
Published Date
Dec 11, 2020
Volume
236
Issue
7
Pages
5098 - 5107
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