The diagnostic value of exosomal miRNAs in human bile of malignant biliary obstructions

Diagnosis of malignant biliary obstruction is complicated and lacks accuracy. Exosomes may be secreted by malignant tumors; intact miRNAs from exosomes might serve as potential biomarkers for the disease.To identify exosomal microRNAs in human bile among benign and malignant biliary obstructions.Bile samples were collected from patients undergoing therapeutic endoscopic retrograde cholangiopancreatography for biliary obstruction. Exosome...