Cyanine mitochondrial dye with slightly selective cytotoxicity against A549 cancerous cells

Delocalized lipophilic cations (DLCs) are known as mitochondria‐addressed molecules. Mitochondria targeting may provide opportunities for tumor detection. DLCs may have antioxidant or anticancer properties. In this study, we focused on the toxicity and localization of 2‐[( E )‐2‐(5‐fluoro‐2‐methyl‐1 H ‐indol‐3‐yl)ethenyl]‐1,6‐dimethylpyridin‐1‐ium iodide (62E2), which has recently been found as a novel cytotoxic fluorescent compound. The...